Question 1

Tropheryma whipplei is characterized by the presence of periodic acid-Schiff (PAS) -staining macrophages, which indicates mucopolysaccharide or glycoprotein, in almost every organ system.Without treatment, this disease is uniformly fatal.Identification is achieved using:

Accepted Answer

A)   enzyme-linked immunosorbent assay (ELIS
A)  .
B)   IFA.
C)   immunoblotting.
D)   real-time polymerase chain reaction (PCR) .E) A) and C)
F) A) and B) D

Question 2

The drug of choice for the treatment of granuloma inguinale, which is a major cause of genital ulcers in India, New Guinea, and part of South America, is:

Accepted Answer

A)   clindamycin.
B)   doxycycline.
C)   imipenem.
D)   gentamycin.E) C) and D)
F) B) and C)

Question 3

The Coxiella burnetii, an acute systemic infection, primarily affects the lungs and can exist in two antigenic states.The reference method that is both highly specific and sensitive and is recommended for identification is:

Accepted Answer

A)   immunofluorescent antibody (IF
A)  .
B)   direct fluorescent antibody (DF
A)  .
C)   Western blot.
D)   latex agglutination.E) A) and C)
F) C) and D) A

Question 4

Of the following organisms, which has a unique developmental life cycle including a replicative form, the reticulate body (RB) , and an extracellular, metabolically inert, infective form, the elementary body (EB) ?

Accepted Answer

A)   Rickettsia
B)   Chlamydia
C)   Ehrlichia
D)   CoxiellaE) A) and B)
F) C) and D)

Question 5

Binary fission within vacuoles divides which of the following forms of Chlamydia?

Accepted Answer

A)   RB
B)   EB
C)   Replicate body
D)   Initial bodyE) B) and D)
F) None of the above

Question 6

The most common sexually transmitted bacterial pathogen and a major cause of pelvic inflammatory disease (PID) is:

Accepted Answer

A)   Rickettsia rickettsii.
B)   Chlamydia trachomatis.
C)   Klebsiella granulomatis.
D)   Coxiella burnetii.E) None of the above
F) A) and C)

Question 7

A prokaryote that differs from most other bacteria with respect to its very small size and obligates intracellular parasitism is:

Accepted Answer

A)   Rickettsia.
B)   Ehrlichia.
C)   Calymmatobacterium.
D)   Coxiella.E) A) and B)
F) A) and C) A

Question 8

A Weil-Felix test was performed on serial dilutions from a patient bitten by a tick.The results obtained were positive for OX-19 and negative for OX-2 and OX-K.Based on these findings, the organism can be identified as:

Accepted Answer

A)   Rickettsia rickettsii.
B)   Orientia tsutsugamushi.
C)   Rickettsia prowazekii.
D)   Rickettsia typhi.E) All of the above
F) A) and B)

Question 9

Which of the following vectors transmit scrub typhus?

Accepted Answer

A)   Lice
B)   Ticks
C)   Fleas
D)   ChiggersE) A) and C)
F) C) and D)

Question 10

Of the following organisms, which can be described as a fastidious obligate intracellular parasite that multiplies by binary fission in the cytoplasm of host cells and infects humans as accidental hosts in most cases?

Accepted Answer

A)   Rickettsia
B)   Chlamydia
C)   Calymmatobacterium
D)   CoxiellaE) A) and B)
F) C) and D)

Exam 43: Obligate Intracellular and Non-culturable Bacterial Agents

Tropheryma whipplei is characterized by the presence of periodic acid-Schiff (PAS) -staining macrophages, which indicates mucopolysaccharide or glycoprotein, in almost every organ system.Without treatment, this disease is uniformly fatal.Identification is achieved using:

Correct Answer
verified
D

The drug of choice for the treatment of granuloma inguinale, which is a major cause of genital ulcers in India, New Guinea, and part of South America, is:

Correct Answer
verified

The Coxiella burnetii, an acute systemic infection, primarily affects the lungs and can exist in two antigenic states.The reference method that is both highly specific and sensitive and is recommended for identification is:

Correct Answer
verified
A

Of the following organisms, which has a unique developmental life cycle including a replicative form, the reticulate body (RB) , and an extracellular, metabolically inert, infective form, the elementary body (EB) ?

Correct Answer
verified

Binary fission within vacuoles divides which of the following forms of Chlamydia?

Correct Answer
verified

The most common sexually transmitted bacterial pathogen and a major cause of pelvic inflammatory disease (PID) is:

Correct Answer
verified

A prokaryote that differs from most other bacteria with respect to its very small size and obligates intracellular parasitism is:

Correct Answer
verified
A

A Weil-Felix test was performed on serial dilutions from a patient bitten by a tick.The results obtained were positive for OX-19 and negative for OX-2 and OX-K.Based on these findings, the organism can be identified as:

Correct Answer
verified

Which of the following vectors transmit scrub typhus?

Correct Answer
verified

Of the following organisms, which can be described as a fastidious obligate intracellular parasite that multiplies by binary fission in the cytoplasm of host cells and infects humans as accidental hosts in most cases?

Correct Answer
verified

Exam 43: Obligate Intracellular and Non-culturable Bacterial Agents

Tropheryma whipplei is characterized by the presence of periodic acid-Schiff (PAS) -staining macrophages, which indicates mucopolysaccharide or glycoprotein, in almost every organ system.Without treatment, this disease is uniformly fatal.Identification is achieved using:

Correct AnswerverifiedD

The drug of choice for the treatment of granuloma inguinale, which is a major cause of genital ulcers in India, New Guinea, and part of South America, is:

Correct AnswerverifiedShow Answer

The Coxiella burnetii, an acute systemic infection, primarily affects the lungs and can exist in two antigenic states.The reference method that is both highly specific and sensitive and is recommended for identification is:

Correct AnswerverifiedA

Of the following organisms, which has a unique developmental life cycle including a replicative form, the reticulate body (RB) , and an extracellular, metabolically inert, infective form, the elementary body (EB) ?

Correct AnswerverifiedShow Answer

Binary fission within vacuoles divides which of the following forms of Chlamydia?

Correct AnswerverifiedShow Answer

The most common sexually transmitted bacterial pathogen and a major cause of pelvic inflammatory disease (PID) is:

Correct AnswerverifiedShow Answer

A prokaryote that differs from most other bacteria with respect to its very small size and obligates intracellular parasitism is:

Correct AnswerverifiedA

A Weil-Felix test was performed on serial dilutions from a patient bitten by a tick.The results obtained were positive for OX-19 and negative for OX-2 and OX-K.Based on these findings, the organism can be identified as:

Correct AnswerverifiedShow Answer

Which of the following vectors transmit scrub typhus?

Correct AnswerverifiedShow Answer

Of the following organisms, which can be described as a fastidious obligate intracellular parasite that multiplies by binary fission in the cytoplasm of host cells and infects humans as accidental hosts in most cases?

Correct AnswerverifiedShow Answer

Correct Answer
verified
D

Correct Answer
verified

Correct Answer
verified
A

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified
A

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified